1 Best Restaurant in Biloxi, Mississippi

Half Shell Oyster House

$$$

Opened in 2011 inside a retrofitted historic bank building one block off Highway 90, this popular Gulf-view restaurant has earned rave reviews and loyal fans for its charbroiled oysters, the signature menu item. With a distinctly New Orleans architectural vibe, the Half Shell Oyster House features a similarly flavored creole menu of oysters prepared six ways, plus fish, chicken, pasta, burgers, and steaks—with or without a kick. Reservations are not accepted from 6 pm–8 pm on weekends to leave room for walk-ins. Guys: check out the oyster-shell walls in the upstairs men's room.